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GCSE Combined Science

Cell Biology

74 questions6 subtopicsAQAEdexcelEduqasOCRWJEC
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What's covered

Cell Transport15
Cell Structure14
Cell Division13
Microscopy11
Specialised Cells11
Stem Cells10

Key facts

1

Cancer is uncontrolled cell division caused by mutations to genes that regulate the cell cycle, producing tumours.

2

Animal cells do not have a cell wall (cellulose walls are a plant-cell feature).

3

Active transport can move substances against a concentration gradient using cellular energy.

4

The main advantage of an electron microscope is far greater magnification and resolution than a light microscope.

5

Ciliated epithelial cells line the trachea and bronchi; their cilia sweep mucus and trapped debris away from the lungs.

6

Adult stem cells are found in tissues like bone marrow and can differentiate into a more limited range of cell types — e.g. bone marrow stem cells form the various blood cell types but not nerves.

7

During meiosis, crossing over exchanges sections of chromatids between homologous chromosomes, creating new combinations of alleles.

8

The cell membrane controls which substances enter and leave the cell.

9

Active transport moves substances against a concentration gradient and requires energy.

10

Electron microscopes can see ribosomes and other tiny organelles that light microscopes cannot resolve.

Sample questions

A taste of the 74 questions in this topic — answers marked. Sign up to practise the full set with spaced repetition.

1Cell Division

What type of cell division produces two genetically identical daughter cells for growth and repair?

  • Binary fission
  • Fertilisation
  • Meiosis
  • Mitosis
2Cell Structure

Which structure is found in plant cells but NOT in animal cells?

  • Cell membrane, cytoplasm, and a nucleus
  • Cell wall, chloroplasts, and a permanent vacuole
  • Cytoplasm, ribosomes, and a cell membrane
  • Mitochondria, ribosomes, and a nucleus
3Cell Transport

What is osmosis?

  • Any molecule moves down a concentration gradient through a membrane.
  • Mineral ions move through a membrane using ATP from mitochondria.
  • Water moves against its gradient using energy from respiration.
  • Water moves through a partially permeable membrane down its gradient.
4Microscopy

What is the main advantage of an electron microscope?

  • Far greater magnification and resolution than a light microscope.
  • It can view living cells, while light microscopes cannot.
  • It is cheaper and easier to use in schools.
  • It produces colour images instead of black-and-white ones.
5Specialised Cells

How is a sperm cell adapted for fertilising an egg?

  • Cilia for movement and glycogen stores instead of mitochondria.
  • Long tail to swim; mitochondria for energy; acrosome enzymes.
  • No cell membrane and no DNA, so it fuses easily.
  • Very large body with thick cell wall to protect DNA.
6Stem Cells

What is a stem cell?

  • A mature cell that has permanently lost the ability to divide.
  • A plant-only cell producing new growth at shoot and root tips.
  • A white blood cell that produces antibodies against pathogens.
  • An undifferentiated cell that can divide and specialise.

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